The USP 6 rotating cylinder is similar to USP Method 1 (the rotating basket). With USP method 6 however, the basket assembly is replaced by a solid stainless steel cylinder. The transdermal patch is fixed to the outside surface of the cylinder. Transdermal testing is carried out at 32°C to reflect the temperature of the skin.
Other variables such as the height setting and sampling requirements are the same as for USP Method.