Paddle Over Disk (USP-5)

With paddle over disc, a transdermal patch is placed either between a glass disc and an inert PTFE mesh, or directly onto a stainless steel mesh. This is placed at the bottom of the vessel, with the mesh facing upwards, under a rotating paddle. Transdermal testing is carried out at 32°C to reflect the temperature of the skin. Other variables such as the height setting and sampling requirements are the same as for USP Method 2.

Useful for

  • Transdermal patches

  • Standard volume

  • 900 ml

  • Temperature

  • 32°C

  • Advantages

  • Standard equipment (paddle) can be used, only adds a stainless steel disk assembly.

  • Alternative

  • "Sandwich" / Watchglass
  • USP 30 footnote:
    “A suitable device is the watchglass-patch-polytef mesh sandwich assembly available as the transdermal Sandwich™”
  • Accepted by the FDA.

    Paddle Over Disc 33mm
    Paddle Over Disc 50mm
    Paddle Over Disc 55mm
    Paddle Over Disc 65mm
    Paddle Over Disc 85mm
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