PRODUCTS

Basket USP Apparatus-1

Adopted in 1970 the rotating basket method of dissolution testing was the first official method. It essentially consists of an approximately 1 inch (25.4mm) x 1 3/8 inch (34.925mm) stainless steel, 40-mesh wire basket rotated at a constant speed between 25 and 150rpm. This method is now called Apparatus 1 (or method 1). The apparatus consists of a metallic drive shaft connected to the cylindrical basket. The basket is positioned inside s vessel made of glass or other inert, transparent material. The vessel contents are kept at a constant temperature by being placed inside a water bath or heating jacket. The solution in the vessel is stirred smoothly by the rotating basket. The USP Apparatus 1 requires a 40-mesh screen unless otherwise specified in the monograph. Other meshes can be used to solve individual problems.

Useful for

  • Capsules
  • Beads
  • Delayed release / enteric coated dosage forms
  • Floating dosage forms
  • Surfactants in media


  • Advantages

  • Breadth of experience (more than 200 monographs)
  • Full pH change during the test
  • Can be easily automated which is important for routine investigations


  • Standard Volume

  • 900/1000 ml
  • 1,2,4 liter vessels


  • Gold plated basket
    Pure gold plating up to 2.5um thickness is allowed by the USP for use in acid media or where the active drug reacts with the plain steel basket. If gold is used, the shaft as well as the basket should be coated. Uncoated baskets deteriorate from contact with acid and they become less rugged and are more likely to distort during assembly on the drive rod.



    Unique identification
    All baskets and shafts should be unique identified, documented, and kept in the same position in the same test assembly for all dissolution runs.

     
    10 Mesh Basket "E" Type
    UL00042
    20 Mesh Basket "E" Type
    UL00043
    30 Mesh Basket "E" Type
    UL00044
    40 Mesh Basket "E" Type
    UL00045
    60 Mesh Basket "E" Type
    UL00046
    80 Mesh Basket "E" Type
    UL00047
    100 Mesh Basket "E" Type
    UL00048
    10 Mesh Basket "D" Type
    UL00049
    20 Mesh Basket "D" Type
    UL00050
    30 Mesh Basket "D" Type
    UL00051
    40 Mesh Basket "D" Type
    UL00052
    60 Mesh Basket "D" Type
    UL00053
    80 Mesh Basket "D" Type
    UL00054
    100 Mesh Basket "D" Type
    UL00055
    Gold Plated Basket
    UL00056
    Stationary Basket
    UL00057
    Felodipine Basket
    UL00058
    10 Mesh Basket Lid
    UL00059
    40 Mesh Basket Lid
    UL00060
    Basket "O" Ring (Set of 6)
    UL00061
    Basket Holder With Clip
    UL00062
    Basket Holder With "O" Ring
    UL00063
    Basket Rod
    UL00064
    Basket Validation Gage Go-No-Go
    UL00065
     
    Basket Stand Moulded Type
    UL00066
    Basket Tray For Baskets
    & Shaft Moulded Type
    UL00067
     
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